Click on links below to access relevant journal articles, including the published clinical trials for LIXIANA® from The New England Journal of Medicine.

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Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial.

Ruff CT et al.

Lancet 2015; Mar 10: doi: 10.1016/S0140-6736(14)61943-7. [Epub ahead of print]

Edoxaban versus Warfarin in Patients with Atrial Fibrillation

Giugliano RP et al.

NEJM 2013; 369(22):2093–2104

Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism

The Hokusai-VTE Investigators

NEJM 2013; 369(15):1406–1415